Mevalonate kinase deficiency (MKD)

The most characteristic signs are:

  • Fever attacks lasting between 3 and 10 days, severe stomach pains, diarrhoea, vomiting, headaches, sore throat and sometimes mouth ulcers (more or less large-sized surrounded by redness and often painful),
  • pain in the muscles,
  • and enlarged neck lymphnodes (like small balls under the skin).
  • Small red pimples are sometimes present on the body at the time of fever attack.

The onset of s ymptoms of MKD almost always begins before the age of 1 year.