;

TNF receptor 1 deficiency (TRAPS)

The most characteristic signs are: 

  • The fever attacks have long duration for several weeks.
  • They are accompanied by intense pain in the muscles recalling the Flu.
  • During crises some patients may have red eyes and swollen eyelids, as well as  throat, stomach and chest pain.
  • On the skin there may be red patches of rather large size, often painful, unique or more diffuse